Ketamine can induce many levels of sedation that are useful in medicine, but it depends on the dose and how it’s administered.

The difference between ketamine sedation and anesthesia is the dose.

In fact, sedation has several levels:

  • Minimal Sedation — Patient is still conscious and can answer questions
  • Moderate Sedation — Alteration of patient’s consciousness, relaxed muscles, but still responding to stimuli
  • Deep Sedation — Someone does not respond easily to stimuli like questions or pain but can be awakened.

Beyond these levels, in a “high dose,” ketamine acts as an anesthetic. A “low dose” of ketamine creates a calming and painkilling effect. The state is useful for certain medical procedures and is sought after by recreational users.


Recreational use of ketamine is often done by snorting small amounts of finely ground ketamine crystals or powder. The powder is absorbed by the mucus membrane in the nasal cavity, entering the bloodstream and the brain. Ketamine Powder

Snorting ketamine is the most common form of administration for recreational users for a reason — it’s quick, (can be) discreet, and shareable.

In this article, we unpack how to snort ketamine, its risks, benefits, safety, bioavailability, and all things related to ketamine insufflation.

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Taking Ketamine Powder: Risks & Side Effects

Snorting ketamine is not without risks. Taking ketamine while driving, swimming, bathing, or in combination with other drugs or alcohol or while engaging in risky behavior can be fatal.

The first order of safety with snorting ketamine is testing the substance to be sure it is indeed ketamine.

While ketamine is frequently used by people in small amounts without issue, it can cause side effects, such as:

At high doses, like the K-hole experience, vomiting can cause you to choke. If you’re seeking the K-hole, always have a trip sitter nearby. If tripsitting someone who may vomit, put them in the recovery position. Combining ketamine with alcohol increases this risk

Extreme cases of abuse often lead to severe damage to the bladder, sometimes requiring its removal.

Individuals with the following conditions should avoid ketamine

  • Personal or family history of schizophrenia or psychosis
  • Cardiovascular disease, such as hypertension
  • Substance use disorder
  • Bladder, kidney, or liver issues
  • Pregnant or breastfeeding

Ketamine can be dangerous (even fatal) if mixed with other substances, particularly downers like alcohol, opioids, and benzodiazepines.

Snorting ketamine can lead to:

  • Nasal irritation and inflammation
  • Difficulty swallowing
  • Reduced sense of smell
  • Hoarse voice
  • Nose bleed
  • Perforated septum (a hole between nostrils) [4]

When snorting ketamine, do not share applicators like straws or rolled bills. Harm reduction experts note the risk of transferring bloodborne viruses through tiny amounts of blood, like hepatitis C or HIV.

 Ketamine Powder Dose

A snorted dose of ket will depend on your tolerance, purity of ketamine, and how your body responds to the substance.

As with any drug, the best advice is to start low and go slow. You can always take more, but not less.

  • Threshold — 5-30 mg
  • Standard — 30-80 mg
  • High — 80-150 mg+

Going beyond the 150 mg mark will bring many people into the K-hole — a place of profound dissociation, which can be enlightening or terrifying. Always have a sitter if seeking the K-hole.

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How to Snort Ketamine Powder

Snorting ket is also called doing ” lines ” or “bumps.”

Always test drugs before consuming them. Little bags or white powder can be easily mixed up. Increasingly, adulterants are found in drugs like ketamine, including fentanyl. Snorting even a small amount of the wrong compound can be fatal.

Once you know you have ketamine, snorting it is a fairly straightforward process:

  • If possible, weigh out the desired dose.
  • Make the finest powder possible. Use a plastic card to press and rub the powder with the flat of the card in a circular motion.
  • Shape the line. The width of a pencil led is a good guide.
  • Use a plastic straw or rolled paper to inhale through your nose. This doesn’t need to be forceful; think of smelling a flower.
  • Wait 5-15 minutes for the effects to kick in before consuming more.

After the ketamine is in your nostrils, it will go down the back of your throat, known as the “drip.” You can swallow or spit out the drip since it doesn’t seem to affect the high.

Rumors circulate that spitting the drip is better for your health, but we are unaware of any evidence supporting this theory.

Snorting Ketamine Powder: Harm Reduction Tips

Usually, ketamine is taken many times throughout a night or event, leading to irritation or damage to the nostrils. Some will use saline solutions to prepare or periodically clean the nostrils. Frequent insufflation will produce excess mucus, potentially lowering absorption.

Others will opt for ketamine nasal spray or even snort small amounts of water and ketamine mixture from their hands. We cover making nasal spray below.

To make a finer powder from ketamine crystals: 

Some mention cooking ketamine, covered below, to create a desirable consistency of ketamine powder.

When using a scale to measure the dose is impractical, one Reddit user mentioned creating “guidelines.” By chalking up several lines, all the same size, and leaving one behind, it’s possible to keep track of the amount you’re doing.

How to Cook Ketamine Liquid to Powder

Ketamine is often found in liquid form as ketamine hydrochloride (ketamine HCl). Hospitals and first responders get ketamine in this form, and illicit ketamine is often transported as a liquid.

Some people prefer to inject ketamine intravenously or intramuscularly. However, injecting is riskier, and converting ketamine from liquid to solid can be done at home.

Often called “cooking,” the process is technically evaporation. The simplest method is to put liquid ketamine into a large flat dish and let the water evaporate for a day or two.

For those who do not want to wait, heating the ketamine HCl in the microwave, oven, double boiler, or even a frying pan can speed up evaporation.

How To Buy Ketamine Without A Prescription

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Outside of clinical use — even off-label clinics — ketamine is illegal.

Criminal punishments aside, contamination in ketamine is rampant, and buying it from unknown sources can be extremely dangerous.

If you decide to purchase ketamine from a clandestine source, always make sure you test it before using it — even if you trust the person who gave it to you. Periodically, the market for ketamine dries up following a major bust or new tightening of prohibition, and contamination becomes even more predominant.

Never take a friend’s word a drug is safe — know for sure using a ketamine drug test kit before you take it.

What’s the Best Way To Get Ketamine?

The best way to get ketamine is to buy from online and Psyttraxx is the best online store to get quality ketamine and other psychedelics.

Ketamine clinics are probably the most effective route for getting high-dose medical ketamine — but they’re expensive. These clinics often charge upwards of $400 per session.

Online ketamine therapy is a cheaper option and is by far the most convenient — but it’s also pretty expensive at around $200 per dose. There are more affordable companies selling ketamine microdoses, but we recommend avoiding these altogether — there’s no evidence this ultra-low dose ketamine offers any real benefits.

Spravato — the ketamine nasal spray, is another good option, but it’s way overpriced compared to an IV clinic — which offers substantially better care. This option is only good if you have insurance coverage.

How Long Does Ketamine Stay In Your System?

The effects of ketamine can last anywhere from 1–3 hours, depending on the dose and form of administration. It can remain detectable in your system for up to 2 days after using it (but usually closer to 24 hours). The exceptions are urine tests and hair tests (14 days and 90 days, respectively).

Effects of snorting ketamine powder occur within 5-15 minutes. The effects peak at 30 minutes, remain active for another 30 minutes, then taper off over the course of an hour. The total duration is between 1 and 3 hours, depending on the dose

Does Ketamine Show Up on a Drug Test?

Standard drug panels don’t look for ketamine, although it’s possible to run specific tests for it.

While ketamine is legal for off-label use, an employer is well within their rights to test for the substance, particularly if they suspect abuse.

However, extra tests represent higher costs, and most employers will only order additional testing if there is suspicion of abuse.

Testing for ketamine generally focuses on its metabolites — the compounds created as the body’s metabolism breaks down ketamine. Some tests focus on the metabolite norketamime or secondary metabolite dehydronorketamine.


Here are some common questions about snorting ketamine we get asked.

1. Is Snorting Ketamine Dangerous?

Yes, overuse can be damaging to the body and lead to addiction. Any substance can be abused, and it’s essential to be conscious and honest about your use when experimenting with substances.

Ketamine doesn’t necessarily lead to serious problems when used sparingly. If drug use is affecting your everyday life, we urge you to talk to someone you trust about your substance use.

2. Can You Overdose Snorting Ketamine?

While it’s rare, an overdose from snorting ketamine is possible. Most overdoses with ketamine involve multiple substances, like alcohol, opioids, and benzodiazepines.

Some overdoses also stem from people unknowingly taking ketamine that contains adulterants like fentanyl. Always get drugs tested, and never use them alone.

Other ketamine-related deaths involve driving, taking baths, and swimming.

If you or someone in your care may be overdosing, contact medical support. Signs of overdose include shallow breathing (less than ten breaths per minute), low/high blood pressure, and heart attack.

Ketamine is not an opioid, and overdose cannot be reversed by naloxone (Narcan).

3. How Long Does Ketamine Stay in Your System?

Snorted ketamine lasts from 15 minutes to over an hour. On average, the whole experience is about 40 minutes.

The duration of effects depends on age, sex, metabolism, genetics, and many other factors.

While ketamine isn’t included in standard drug panels, it can be detected with specialty testing. Depending on the test, ketamine and its metabolites can be detected for up to 14 days in urine or up to 3 months with hair follicle testing

4. How Long Does Ketamine Withdrawal Last?

After a single ketamine treatment for depression or other mental health concerns, there may be some lingering side effects like nausea, fatigue, dizziness, or confusion. These typically dissipate with a good night’s sleep.

For long-term users of ketamine, more severe withdrawal may occur. Physical dependency doesn’t appear to be an issue, but heavy users report intense cravings, anxiety, sweating, abdominal pain, and other symptoms.

5. How Long Does Ketamine Last for Depression?

Ketamine’s effects on depression take hold in 24 hours. While effects persist long after an effective dose leaves the body, benefits can be sustained. However, how long they last depends on the dose, frequency, and if the treatment is in combination with therapeutic support.

6. How Long Does Ketamine Pain Relief Last?

Ketamine infusions for pain can last about two weeks. People with chronic pain have varying degrees of relief, and the source of the pain seems to play a role. For example, those suffering from fibromyalgia pain have reported relief for up to one year.


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