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1P-LSD is a synthetic chemical nearly identical to LSD in its effects. Read our ultimate guide to learn about 1P-LSD and what to expect on a 1P-LSD trip.

P-LSD is an illegal substance in some places, and we do not encourage or condone the use of this substance where it is against the law. However, we accept that illegal drug use occurs, and believe that offering responsible harm reduction information is imperative to keeping people safe. For that reason, this guide is designed to ensure the safety of those who decide to use this substance.

However, with recent findings that 1P-LSD is converted to LSD at a rate of nearly 100%, the psychoactive dose would be identical to that of LSD:

  • Microdose — 10–20 micrograms
  • Threshold Dose — 25–40 micrograms
  • Standard Psychoactive Dose — 80–200 micrograms
  • Heroic Dose — 200–400 micrograms
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By now, you’re probably familiar with LSD (lysergic acid diethylamide). It’s the quintessential psychedelic substance alongside the active ingredient in magic mushrooms — psilocybin. Buy 1p-lsd Alabama, USA.

What you may not be familiar with is that there are actually dozens of analogs of LSD that have virtually identical effects. 1p-lsd for sale

1P-LSD is one such analog. The molecular difference is subtle, and recent research even suggests 1P-LSD is a prodrug of LSD. This means that when you take 1P-LSD, it’s converted to LSD to produce psychedelic effects.

1P-LSD is legal in Canada and held in a legal grey area in the United States. Where to buy 1p-lsd online in Alaska, USA.

Here’s everything you need to know about 1P-LSD. buy 1p-lsd

What is 1P-LSD?

1P-LSD stands for 1-propionyl-lysergic acid diethylamide. It’s a derivative of LSD — which essentially means it’s a modified version of the classic LSD-25 that Albert Hofmann discovered in 1943. How to buy 1p-lsd online in Arizona, USA.

This molecule is differentiated from LSD by a propionyl group attached to the nitrogen molecule in the indole portion of LSD. The central indole molecule of LSD is the characterizing element of the molecule that’s shared with all other tryptamine-based psychedelics (such as DMT or psilocybin). 1p-lsd etsy

1P-LSD itself is only mildly psychedelic. It has a 67-fold less binding affinity for the 5-HT1A receptors, 13-fold less activity at the 5-HT2A receptors, and a 3.5-fold increase at h5-HT2C receptors than LSD-25. Order 1p-lsd online in Arkansas, USA.

However, 1P-LSD is a prodrug for LSD, which means it’s converted to LSD by the liver, which then goes on to produce psychoactive effects [2]. The bioavailability of LSD from 1P-LSD is nearly 100%. 1p-lsd buy

1P-LSD: Specs & Technical Details

Active Ingredient 1-propionyl-lysergic acid diethylamide
Level of Risk Low
Other Names Legal Acid
Most Common Side-Effects Anxiety & paranoia
Duration of Effects 7 – 11 hours
Legality Not Scheduled In Most Countries (Legal Grey-Area)

Originality Of  1P-LSD ?

Since the prohibition of LSD and other psychedelics in 1966, chemists have been seeking to discover new psychedelicresearch chemicals” or “designer drugs.1p-lsd safety.

Researchers like Alexander Shulgin and Dr. David E. Nichols (Purdue University) have made a lot of progress over the years. Buy 1p-lsd online in California, USA.

It’s unclear when 1P-LSD was first invented and by whom — but it was first officially reported in 2015 by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Where to buy 1p-lsd.

This compound entered the market as a “legal LSD alternative” in the mid-2010s without any previous mention in scientific literature. Whoever invented it didn’t publish anything about it and has made no attempt to take credit for their discovery, is 1p-lsd legal.

Other Lysergic Acid Dimethylazetidide

& Derivatives

 Dosage of 1P-LSD?

The dose of 1P-LSD is equivalent to LSD. There have never been any studies on the effective dose of 1P-LSD. Where to buy 1p-lsd online in Colorado, USA.

However, with recent findings that 1P-LSD is converted to LSD at a rate of nearly 100%, the psychoactive dose would be identical to that of LSD: is 1p-lsd legal in usa

What Does 1P-LSD Feel ?

The effects of 1P-LSD are virtually identical to that of LSD. The only difference is that it can take a little bit longer for the effects to kick in. This is because the 1P-LSD needs to first be metabolized by the liver and turned into LSD. 1p-lsd blotters. How to buy 1p-lsd online in Connecticut, USA.

The experience can vary widely depending on your internal mental state. If you’re depressed or anxious going into the experience, 1P-LSD is going to inflate this even further. Likewise, if you feel excited, positive, and curious, 1P-LSD is going to expand this state of consciousness even further. 1p-lsd reddit.

This is exactly why the concept of set (mindset) and setting (the environment and people you’re with during the trip) is so important. Going into the experience with a negative attitude, which can include fear, anxiety, or depression, will ultimately lead to a more challenging experience and may even pose psychological harm. Order 1p-lsd online in Florida, USA.

The positive effects of 1P-LSD and other LSD analogs:

The negative effects of 1P-LSD and other LSD analogs:

These negative effects can’t always be avoided, but they can be significantly reduced by following our guidelines for the responsible use of psychedelics. Purchase 1p-lsd online in Georgia, USA.

Duration 1P-LSD In The Body?

1P-LSD lasts roughly the same amount of time as LSD (6 – 10 hours).

After taking 1P-LSD, it’s converted to LSD. This happens quickly but prolongs the amount of time needed for the effects to appear. LSD usually takes less than 30 minutes to kick in, while 1P-LSD can take up to an hour and a half (usually around an hour). This also extends the total duration of the trip. 1p-lsd canada.

The estimated duration of effects for acid is 6 to 10 hours, which means 1P-LSD is roughly 7 to 11 hours when you account for this difference.
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How to Consume 1P-LSD

1P-LSD is taken the same way as LSD. It’s spread out over a square of blotter paper and then held under the tongue for 10 or 15 minutes before swallowing it whole. Purchase 1p-lsd online in Idaho, USA.

The active ingredients are absorbed through the capillaries under the tongue, directly into the bloodstream.

Most people hold LSD under the tongue for faster onset of effects because it allows it to enter the bloodstream directly — rather than having to travel through the digestive tract first. 1p-lsd purchase.

However, 1P-LSD may actually kick in faster if you swallow the tab instead. Buy 1p-lsd online in Illinois, USA.

This is because, unlike acid, this psychedelic needs to be activated by the liver. When you absorb compounds like this through the gut, they’re sent directly to the liver, which does a “first-pass metabolism” before entering the systemic circulation. 1p-lsd usa.

Potency Of 1P-LSD Compared To Other Psychedelics?

1P-LSD is one of the strongest psychedelics, gram for gram, on Earth. This is a title held by all psychoactive LSD derivatives, which are profoundly psychoactive at sub-milligram doses. 1p-lsd blotter.

For example, the dose of 1P-LSD is around 200 micrograms, which is about 0.2 milligrams. Compare this to psilocybin (the active ingredient in magic mushrooms), which is closer to 10 milligrams. 5-MeO-DMT, the active ingredient in the Bufo alvarius toad (another powerful psychedelic), has a dose of around 8 milligrams, and N,N-DMT, the active ingredient in ayahuasca, is nearly 50 mg. 1p-lsd online. Order 1p-lsd online in Indiana, USA.

1P-LSD vs. LSD-25

LSD-25 is the classic version of LSD invented by Albert Hofmann in the 1940s. It’s the compound that was popularized during the 1960s and beyond by people like Timothy LearyRichard Alpert (Ram Dass), Nicolas Sand, Tim Sully, Ralph Metzner, and others. 1p-lsd vendor. Buy 1p-lsd online in Iowa, USA.

Compared to LSD-25, 1P-LSD is virtually indistinguishable. There are some reports that 1P-LSD is weaker, others suggesting it’s stronger. The consensus is that the two are identical in terms of their effects and dosage. 1p-lsd for sale in Kansas, USA.

1P-LSD vs. AL-LAD

AL-LAD (N6-allyl-6-norlysergic acid diethylamide) is another derivative of LSD-25 with a similar chemical structure as 1P-LSD. 1p-lsd duration. Where to buy 1p-lsd online in Kentucky, USA.

The dose and overall experience are very similar, but with a few subtle subjective differences. How to buy p1p-lsd online in Louisiana, USA.

For example, AL-LAD is thought of as being a more mellow version of acid. It has a stronger visual aspect, but it’s less introspective. This means it’s going to be a bit easier to handle from a philosophical perspective and less likely to result in issues with ontological shock or existential anxiety — something that can stem from the psychedelic experience. 1p-lsd where to buy.

1P-LSD vs. LSA

LSA (lysergic acid amide) is the active ingredient in Hawaiian baby Woodrose and morning glory vine It’s very similar to the effects of LSD-derivatives like 1P-LSD but with a few key differences. Buy 1p-lsd near me in Maine, USA.

For one, LSA is less potent than 1P-LSD. The standard psychoactive dose is around 800 micrograms rather than 200 for 1P-LSD. Can i buy 1p-lsd in Massachusetts, USA.

Secondly, the LSA experience is less introspective and psychedelic and more lucid and sedative. It often leads people to fall asleep where they experience complex, vivid, and memorable dreams. Even while awake, the experience feels very dreamlike.

1P-LSD vs. ALD-52

1P-LSD is a homolog of this ALD-52, which means it’s virtually identical aside from having an extra carbon atom. Buy 1p-lsd online in Michigan, USA.

Technically speaking, 1P-LSD has a propionyl group attached to the nitrogen atom in the indole group, while ALD-52 has an acetyl group instead. Where to purchase 1p-lsd online in Minnesota, USA.

The effects of these two molecules are essentially identical. How to buy 1p-lsd online in Mississippi, USA.

1P-LSD vs. ETH-LAD

ETH-LAD (6-ethyl-6-nor-lysergic acid diethylamide) is the strongest member of the lysergamide psychedelics (there’s some debate to this).

ETH-LAD is considered to be roughly 20% stronger than 1P-LSD when taken at the same dose. It has stronger visuals and produces a strong sense of connection and introspection. 1p-lsd for sale in Missouri, USA.

The downside of this compound is that it also tends to cause some negative physical side effects — such as stomach upset and increased urination. This can lead novice users to panic and experience a more challenging trip. buy 1p-lsd online.

Because of this, ETH-LAD is not recommended for people who are new to psychedelics. 1P-LSD is a better option for these people, and is much less likely to cause a “bad trip.” Buy 1p-lsd in Montana, USA.

1P-LSD vs. PRO-LAD

PRO-LAD (6-propyl-6-nor-lysergic acid diethylamide) was discovered sometime in the early to mid-80s by Dr. David Nichols and his team at Purdue University. Get or buy 1p-lsd online in Nevada, USA.

This compound is slightly weaker than 1P-LSD — but most people won’t be able to tell the difference between these two psychedelics. 1p-lsd buy online.

The main difference, as pointed out in various trip reports, is that PRO-LAD has a stronger body-high component than 1P-LSD.

1P-LSD vs. LSZ

LSZ (lysergic acid 2,4-dimethylazetidide) is the second strongest lysergamide psychedelic. It’s similar in potency to ETH-LAD, but less likely to result in physical side effects. 1p-lsd for sale in New Hampshire, USA.

Compared to 1P-LSD, LSZ produces a stronger “emotional” experience. Many people who take this psychedelic report a strong sense of connection and empathy with others. Buy 1p-lsd in New Jersey, USA

This effect is also found with 1P-LSD, but not quite as intense. 1p-lsd sale.

Is 1P-LSD Safe?

There have never been any clinical studies on 1P-LSD to confirm its safety in humans, and this compound has only been on the market for a couple of years now. 1p-lsd for sale New Mexico, USA.

With that said, there have never been any reported cases of toxicity or deaths associated with this compound. Preliminary research suggests it shares the same effect profile and safety as LSD-25 — a compound with copious amounts of research proving the high safety incidence of this compound. 1p-lsd research chemical. 1p-lsd for sale Texas, USA.

The Respectful Usage of Psychedelics

As is the case with all psychedelics, it’s critical that you understand how to stay safe with these compounds before you begin. While there isn’t much of a risk in terms of physical side effects, these substances carry the risk of psychological harm. 1p-lsd legal status usa.

People with a history of psychosis, schizophrenia, or other mental illness should always consult a psychologist before using psychedelics. While there’s some indication these compounds can help treat mental illness, this needs to be done in a controlled setting under the supervision of a psychotherapist. In this environment, it’s more likely that LSD-25, psilocybin, or 5-MeO-DMT will be used instead of 1P-LSD due to a lack of clinical research. buy 1p-lsd us. where to get 1p-lsd.

Damages of Adulteration

One of the benefits of 1P-LSD is its lighter legal restrictions. While this psychedelic isn’t technically legal, it isn’t illegal either (in most places). This means it’s easier to find a legit supplier than it is for overtly prohibited compounds. You can order 1P-LSD from reputable names like www.psyttraxx.com, or other brand name suppliers, which significantly decreases the chance of adulteration with potentially harmful compounds. buy 1p-lsd canada.

You don’t need to use the black market to buy this stuff. Blackmarket vendors dramatically increase the risk of ordering fake LSD, which often use NBOMe compounds instead — which are dangerous. There have been many deaths associated with this compound in the past. 1p-lsd for sale in Tennessee, USA.

No matter where you buy 1P-LSD, you should test it using a reagent drug testing kit. Here’s how to do it. Buy 1p-lsd in Virginia, USA.

How To Test 1P-LSD And Where To Get 1p-lsd

You only need a small sample to do this effectively, so you aren’t really wasting any money or doses. Just a small sliver of one of your tabs is enough to perform the test. Where to purchase 1p-lsd in South Dakota, USA.

Substance tests aren’t going to tell you the quality of a tab, but they will tell you if certain compounds are in it or not. The only dangerous compounds that are potent enough to fit on a single blotter paper are LSD and its analogs, NBOMe, or DOMx compounds. Buy 1p-lsd in West Virginia, USA.

It’s always a good idea to run multiple substance tests for LSD and 1P-LSD. The ideal would be all four mentioned below, but if you’re only going to run one or two, the Ehrlich and Marquis are the most important.
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1. Ehrlich Test

This will show you whether the tab contains indole alkaloids (LSD, 1P-LSD, AL-LAD, or other derivatives) or not. If you only run one test, this is the one. Where to buy 1p-lsd in Washington, USA.

Place one drop on a small sliver of the tab and wait for it to change color. It should turn purple or dark pink. LSD-25 usually turns right away, while 1P-LSD takes longer (up to 3 minutes).

If there’s no color change, your sample probably doesn’t contain any indole alkaloids and is therefore unsafe to use. How to buy 1p-lsd in Utah, USA.

2. Marquis Reagent

The Marquis reagent will identify amphetamines, NBOMemescaline, and other substances in your sample. If it turns green, it likely contains NBOMe compounds and should be thrown out.

Follow the chart included in your Marquis test kit for the detection of other compounds.

3. Hofmann Reagent

It’s always a good idea to run two or more tests with different reagents just to make sure. The Hofmann reagent is used to differentiate certain indole alkaloids.

If the sample turns purple, it’s likely an LSD-derivative. If it turns green, it’s 5-MeO-DMT; if yellow, it’s N,N-DMT.

4. Mecke Reagent

The main role of the Mecke reagent is to determine whether there are any opiates in the sample. Since most opiates aren’t strong enough at sub-milligram doses, and the experience of these substances is nothing like LSD, it’s very unlikely for there to be any opiates in the sample.

This test is extra, just to be safe. It’s easy to run the Mecke test to make sure the sample doesn’t contain ultra-potent forms of opiates like fentanyl or kar-fentanyl.

If the Mecke reagent turns blue, it means the sample contains opioids and should therefore be avoided.

Technically, 1P-LSD isn’t listed as a controlled substance in either Canada or the United States.

In the US, 1P-LSD could be considered illegal by the DEA under the Federal Analog Act because of its similarity to LSD-25. However, there have yet to be any convictions for the possession of 1P-LSD, and the DEA has never officially mentioned or made any statements about this compound.

Some countries in Europe have added 1P-LSD to their list of prohibited substances, including:

RelatedList of legal psychoactive substances in the US, Canada, and the UK.

Summary: What’s The Future of 1P-LSD?

This psychoactive substance is virtually identical in its effects to LSD. It’s a prodrug of LSD-25, which means it’s converted into LSD by the liver, which then goes on to produce psychoactive effects.

Because LSD is banned, and 1P-LSD isn’t (in most places), it’s used the exact same way as LSD.

As more countries find out about this analog, they’ll likely move to place it under the same regulations as LSD.

More liberal countries, like Canada, are unlikely to make this change as laws are already moving towards legalizing LSD anyway. This compound is not dangerous, and there’s no indication it’s going to pose any additional risk to society. We’ll likely see more of this compound in the near future until LSD-25 becomes legal.

LSD-25 is easier to produce and has a faster onset time than 1P-LSD. When you consider that the two have the same experience, LSD is the slightly better option.

Street Names For LSD

LSD has been around for over 60 years now and has accumulated many nicknames over the years.

Here are some of the most prominent names for LSD:

Psyttraxx Safe LSD Guidelines

  • 📚 Learn the four pillars of responsible psychedelic use — set, setting, sitter, & substance
  • 👀 Know your dose — the standard dose for LSD is about 80 μg
  • 🧫 Test your substances — always test your LSD with a reagent test kit before you start
  • ⏱️ Know the timeline — the effects of LSD are going to last between 7 and 12 hours
  • 👥 Have a trip sitter nearby — someone you trust who remains sober throughout the experience
  • 🧪 Don’t mix — it isn’t safe to mix LSD with other drugs, medications, or alcohol

Dosage of LSD? (LSD Dose Calculator)

The most common dose for LSD is about 80 micrograms — which is the average amount of LSD in a standard square of blotter paper (+/- 10%).

Depending on the manufacturer, the dose per blotter square can range from about 20 mcg of LSD to 100 mcg.

The usual dose is to take one blotter square at a time. Some people will take two or even three doses. Only people with a lot of experience using LSD should even consider taking more than one square at a time. It’s easy to underestimate the effects of LSD until it’s too late.

Many people will take one square and prematurely take another after an hour when the effects aren’t “strong enough.” Sixty minutes later, you’ve got two full doses of LSD. Once you’ve taken the LSD, you can’t un-take it. You’ll feel the effects no matter what you do — so make sure you don’t take too much.

Microdosing

(10 – 25 micrograms)

Any dose below the psychoactive threshold is considered a microdose. This means the dose isn’t strong enough to make you hallucinate.

The threshold for LSD is 25–50 mcg — so most people will take around half or less of that as a microdose (10 – 25 mcg). The purpose of microdosing isn’t to “trip.” The main benefits of microdosing appear gradually over the course of several weeks or months.

There are a few different philosophies on the dosage schedule while microdosing. The most common is the protocol outline by Dr. James Fadiman — a prominent psychotherapy researcher. He sought to standardize microdosing to make it easier to research.

Dr. Fadiman’s protocol is to take a microdose of LSD every third day for a full month.

You can microdose for longer than this but should never do more than three months at a time before taking an extended break for at least a month.

LSD dosage schedules:

The Main Psychoactive Dose

(80 – 200 micrograms)

The average psychoactive dose of LSD is very low — around 80 to 200 micrograms. Even a dose of 20 mcg is enough to produce subtle changes in perception.

The high potency of acid makes measuring the dose difficult. A single drop of acid that’s been diluted for making blotters contains around 70 mcg.

However, a single drop of an undiluted LSD solution could contain as much as 70,000 mcg.

Instead of measuring out drop doses, manufacturers dilute and coat small pieces of paper with LSD and cut them into squares for individual doses. This is referred to as blotter paper.

These paper squares are then placed in the mouth and held there to allow the active ingredient to absorb through the mouth’s mucus membranes.

It’s hard to know what the exact dose is for a single square of blotter acid paper. Factors like how the LSD was stored, whether it was exposed to sunlight or not, and the potency of the acid used to make it can all affect the dose per blotter paper.

You can get a rough gauge on the dose per piece based on its effects. If you or someone else has taken acid cut from the same sheet of blotter paper, you’ll be able to get an idea if it’s on the high-end of the dose (100 mcg LSD) or the lower-end (20 mcg). If you’re not sure, it’s wise to start with just a single piece rather than underestimating the effects and taking too much.

Heroic Dose – Buy 1p-lsd Canada

(200 – 400 micrograms)

A heroic dose is considered any amount above 200 micrograms. These doses are powerful and produce dramatic shifts in the perception of reality. At this dose, you’re likely to experience dissociative thoughts, loss of ego, visual and auditory hallucinations, and out-of-body experiences. While this dose can provide incredible insights and introspective benefits, it also brings a much higher risk of a “bad trip”.

LSD Tolerance – 1p-lsd price

The body forms a tolerance to all tryptamine psychedelics relatively quickly. This includes LSD, DMT, LSA, and psilocybin.

Tolerance means the body becomes resistant to the effects of a drug. You’ll need to take a larger dose the second time you take it to match the intensity of the initial dose.

Tolerance to LSD usually develops after a single dose and can take two weeks to reverse entirely.

If you take a 100 mcg dose of acid today, you’ll need to take roughly 280 mcg tomorrow to experience the same intensity of effects. However, if you wait for about two weeks, you’ll only need to take 100 mcg to get the same effects all over again.

 LSD Tolerance Form?

Compounds like LSD push the balance of receptor activity outside normal parameters. More specifically, LSD activates the 5-HT2A receptors in the brain — causing psychoactive effects. The activity of 5-HT2A goes so far outside the normal range; the body automatically makes changes to reduce the effect.

In order to reduce the activation of these receptors, the body will “hide” some of them. The next time you take LSD, fewer receptors are available for it to exert its effect — producing less impact.

Over the course of 10-14 days without the drug, these receptors will become “unhidden,” and LSD has the same level of impact it had the first time all over again.

Also see: Is LSD Addictive?

LSD Tolerance Calculator

Check out this simple LSD tolerance calculator to help you find the approximate dose to overcome the effects of tolerance when using LSD more than once in a two-week window.

*Note, aside from microdosing, it’s recommended that you avoid taking LSD more than once every two weeks.

This calculator is only able to provide an estimate. Please do not be deceived by the apparent precision of the numbers. For the best experience, let 2 weeks pass between each trip, tolerance should be back to normal after 14 days.

What Does LSD Feels?

Every LSD experience is unique. The effects of the drug feed off your own thoughts and imagination, so the direction a particular trip can take depends on how you’re feeling, the stimuli in your environment, and the people you’re with.

In general, the effects of LSD are usually positive. While it’s possible to have a negative experience (aka, a bad trip), the right preparation (positive mindset, comfortable setting, and a trip sitter) can dramatically reduce the chances of this happening.

Most people report introspection, laughter, and creative insight while taking LSD.

Many of these experiences resonate with people for years after the experience — such as realizing the importance of some of your personal relationships, recognizing toxic thought patterns, and more.

LSD can produce the following feelings:

Not all of the effects of LSD are positive. It’s important to be aware of the negative effects that can arise periodically throughout the trip. If these feelings appear, it’s important to remember that they’re only temporary. As soon as you stop focusing on them, they tend to disappear. Resisting these feelings only makes them worse.

Having a trusted guide with you during your trip — especially if using higher doses — is the most effective way to avoid or dissolve negative feelings during the trip.

Some of the more negative feelings that can arise include:

How LSD Feels According to Dose

LSD Trip Duration Timeline: When Does it Start And How Long Does it Last?

Acid takes around 30 to 60 minutes before it starts to kick in. If you hold the blotter paper under your tongue, it may be even faster.

Acid is one of the longest-lasting psychedelics — in some cases providing psychoactive effects for up to 12 hours. The average duration is closer to 7 hours before you’re about 95% back to normalResidual effects can linger for several more hours, involving feelings of introspection and mild visual distortions.

Here’s what a typical timeline for an acid trip looks like:

T0: The Initial Dose

This is when you first take LSD — marking the start of the journey.

T30: Onset Of Effects

Mild effects may start to appear, starting with a tingling sensation in the stomach. By T60, you’ll begin to see some visual perception changes (objects appear to be moving or vibrating). This is usually accompanied by laughter and giddiness.

T120: Peak Effects

Two hours in, the effects will be blatantly obvious. You may feel euphoric, giggly, and introspective. You’ll be experiencing both visual and auditory hallucinations at this time.

The effects of the drug can be quite intense around this time. This is the period where the heavier side of acid happens. You may experience dissociative thoughts, ego death, and in some cases, out-of-body experiences.

This is the most critical stage to have a trip sitter nearby to help you through any challenging experiences. The hallucinations and dissolving of the ego can cause paranoia, anxiety, and fear. Taking steps before taking LSD — such as finding a trusted trip sitter and finding an environment that’s comfortable and safe — is the best way to avoid problems during the peak effects.

T240: The Slow Downhill Fade

Around the four-hour mark, your trip will have already reached a climax and will start to decline.

You’ll go through periods of high intensity, followed by periods of lower intensity. This waxes and wanes over the next three hours, each time reaching a lower “peak” at the top of the wave.

T360: The Comedown

By hour six, the effects will be dramatically reduced. Some people find they’re back to normal by this time; others may still be experiencing residual effects from the drug.

This period remains full of introspective thoughts as you replay the experience you just went through. Many people feel very relaxed at this point and usually end up in a comfortable position lying or sitting down as you ponder the experience you just went through.

You’ll feel lazy and relaxed — but not tired. This is a great time to journal or talk about your experience with the rest of your group.

T600: The End of the Trip

This is the 10-hour mark. The majority of people will be completely back to normal at this point. Most people will start to feel sleepy by this point as the brain seeks the opportunity to recharge. You’ve spent the past 10 hours exploring, moving around, and thinking at a high level. This is a good time to get some rest and get a fresh start tomorrow.

LSD is illegal in most parts of the world. It’s listed as a Schedule I drug on the UN Convention on Psychotropic Substances (1971). This means all countries taking part in this convention are expected to include LSD on their prohibited substances list.

RelatedList of legal psychoactive substances.

There are currently no countries where LSD is considered legal — however, there’s a growing list of countries, states, and municipalities that have moved to decriminalize LSD.

Decriminalization doesn’t make a substance legal — it just removes the penalties for being in possession of personal amounts of the drug.

LSD Decriminalized Countries In:

Europe

North & South America

Local States & Municipalities

LSD Safety?

There are over 60 years of research to prove LSD is both non-toxic and non-addictive. There have never been any reported overdose cases from people taking too much LSD, and there’s no indication of addiction to LSD. Tolerance formation is possible in people who take LSD often — prompting them to take larger doses to get the same effect.

The best way to assess the toxicity of a drug is to find the LD50. This term in medical research describes the amount of a drug needed to kill roughly 50% of the study participants (usually mice).

There has yet to be an established LD50 for LSD. Even exceptionally high doses of the drug are non-lethal.

In the 1970s, a group of party attendees mistakenly snorted between 1000 and 7000 micrograms of LSD in powder form after mistaking it for cocaine. This is equivalent to taking roughly 100 doses of acid at once. Some of the people in this group experienced problems with bleeding in the digestive tract, vomiting, and temporary comatose states. Everybody in this group survived the incident unharmed.

Despite the high level of safety, there are some potential risks to using LSD. During the trip, visions and hallucinations can cause bouts of anxiety, paranoia, and intense fear —some of which can cause long-term mental harm.

Another long-term (albeit rare) side effect that can result from LSD use is hallucinogen-persisting perception disorder (HPPD). initial trip.

LSD Side Effects

There are two different categories of side effects from LSD — physical side effects (changes in body metrics like temperature or heart rate) and psychological side effects (changes in perception, mood, and mental condition).

Physical Side Effects of LSD

Psychological Side Effects of LSD

Suggested Reading: What Are The Long-Term Effects Of LSD?

How Is The Potency Of LSD Compare To Other Psychedelics?

LSD is considere moderate in terms of strength. It produces much less psychoactivity than a drug like DMT or salvia and more psychoactivity than others like mescaline or marijuana.

LSD is most comparable in terms of effects to magic mushrooms.

You’re unlikely to experience out-of-body experiences on LSD unless you take exceptionally high doses (not recommended).

LSD vs. Magic Mushrooms

LSD is very comparable to magic mushrooms in terms of effects. Both LSD and the active ingredient in magic mushrooms (psilocybin) share a very similar structure and interact with the same receptors in the body.

The difference in these two compounds is subtle — mushrooms tend to have a stronger “body high” and have a shorter duration of effects (about 4 – 6 hours). LSD is more “mental”, producing striking changes in visual and auditory sensory perception.

The psychoactive dose is similar for both compounds — starting at around 20 mcg of pure LSD or pure psilocybin.

LSD vs. DMT

LSD and DMT (dimethyltryptamine) target the same receptors in the brain. Low doses of DMT share many similarities with LSD, and very high doses of LSD are similar to DMT.

DMT has a much higher chance of producing out-of-body or transcendental experiences — stripping away the ego and forcing introspection.

LSD Vs. Mescaline

Mescaline is a psychoactive alkaloid produced in several species of cacti, including peyote and San Pedro. The effects of this compound are very similar to LSD, but with a few distinct differences.

While LSD and mescaline produce kaleidoscope patterns in vision, mescaline has stronger visuals in low-light environments or while the eyes are closed. Mescaline also produces a unique geometricization effect — causing 3-dimensional objects to appear flat and distorted.

LSD vs. LSA

LSA stands for d-lysergic acid amide — it’s often referred to as ergine. Both LSD and LSA are similar in terms of effects and chemical structure.

Both compounds are classified as ergoline alkaloids (alkaloids extracted or derived from the ergot fungus). LSA is naturally-occurring and can be found in plants and fungi such as ololiuhqui, Hawaiian baby Woodrose (Argyreia nervosa), sleepy grass (Achnatherum robustum), and morning glory seeds (Ipomoea violacea). LSD is a synthetic version derived from other alkaloids in the ergot fungus.

LSA is different from LSD in that it’s also a sedative and produces a much milder trip overall compared to LSD. It produces a feeling described as being heavy. LSA is also much more inconsistent in terms of its intensity.

Psychedelic Research on LSD

LSD For Anxiety

So far, several tryptamine-based psychedelics have been shown to produce a substantial improvement in anxiety symptoms over the years. This includes psilocybin from magic mushrooms, DMT, and LSD. This effect stems from a “resetting” of the default mode network (DMN).

A Swiss study explored the effects of LSD in a clinical setting on ten patients diagnosed with a life-threatening disease. This study’s results were remarkable — after just one psychoactive dose, 66% of patients reported an increase in quality of life, and 78% noted a noticeable reduction in anxiety levels.

LSD And Addiction

Researchers have been exploring the effects of LSD and other psychedelics for addiction treatment since the 1960s.

LSD was shown to offer particular improvement for the treatment of alcohol addiction.

In 2012, a review paper analyzed the results of six trials exploring the impact of LSD on alcoholism. The studies included in the trial were conducted between the years 1966 and 1970 [9]. In total, 325 patients were treated with LSD, and 211 received placebo control. All patients were administered a single dose that ranged from 210 to 800 mcg of LSD.

The study reported a dramatic reduction in alcoholic cravings at the first follow-up treatment, which was sustained at the final 6-month follow-up. In total, 59% of the LSD patients saw significant improvement in their alcoholism.

LSD For Cluster Headaches & Migraines

LSD is a sub-member of the larger class of compounds called ergotolines — which are derived from the ergot fungus. Several of these compounds have proven useful as a treatment for cluster headaches and migraines.

Function Of LSD 

The chemical structure of LSD is similar to serotonin — which is one of the most influential neurotransmitters in the brain. Serotonin is responsible for regulating mental processes such as mood, arousal, eating habits, digestion, and much more.

The similarities in structure allow LSD to interact with the serotonin receptors. In particular, LSD targets 5-HT2A and 5-HT2C receptors. These receptors are responsible for the psychoactive effects of LSD and other tryptamine-based psychedelics (such as DMT or psilocybin).

LSD is different from other psychedelics because it can also activate the dopamine D2 receptors.

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